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Updated: Sep 25, 2026

Evaluation of Hemisphere Lateralization with Bilateral Local Field Potential Recording in Secondary Motor Cortex of Mice
Published on: July 31, 2019
Long distance communication in the human brain: timing constraints for inter-hemispheric synchrony and the origin of
Francisco Aboitiz1, Javier López, Juan Montiel
1Departamento de Psiquiatría, Facultad de Medicina, Pontificia Universidad Católica de Chile. Marcoleta No. 387, 2o Piso, P.O. Box 114-D, Santiago 1, Chile. faboitiz@puc.cl
Abstract:
Analysis of corpus callosum fiber composition reveals that inter-hemispheric transmission time may put constraints on the development of inter-hemispheric synchronic ensembles, especially in species with large brains like humans. In order to overcome this limitation, a subset of large-diameter callosal fibers are specialized for fast inter-hemispheric transmission, particularly in large-brained species. Nevertheless, the constraints on fast inter-hemispheric communication in large-brained species can somehow contribute to the development of ipsilateral, intrahemispheric networks, which might promote the development of brain lateralization.
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