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A memory GAP
1Massachusetts General Hospital Cancer Center and Harvard Medical School, Charlestown, MA 02129, USA. settleman@helix.mgh.harvard.edu
Trends in Neurosciences
|June 12, 2003
Abstract:
Pavlovian conditioning of the response to fear has provided an important model for memory formation in mammals. Several studies have begun to identify the key signal-transduction components that provide the molecular basis for this complex neural process. A recent report has revealed that the Rho GTPase and its regulator p190 Rho-GTPase-activating protein (p190 RhoGAP) also play an important regulatory role in fear memory formation.