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[Non conventional transmissible agents and emerging viruses].

O Garraud1

  • 1EFS, Auvergne-Loire, 25, avenue Pasteur, 42023 cedex, Saint-Etienne, France. Olivier.Garraud@univ-st-etienne.fr <Olivier.Garraud@univ-st-etienne.fr>

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|June 12, 2003
PubMed
Summary

Blood transfusions can transmit rare or unknown infectious pathogens, posing risks to recipients. Precautionary measures are essential due to varying pathogen consequences and recipient immune status.

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Area of Science:

  • Infectious diseases
  • Transfusion medicine
  • Immunology

Context:

  • Bacterial contamination is the most common cause of post-transfusion infections.
  • Routine screening detects most known infectious agents in blood donations.
  • Uncommon or unknown pathogens present a unique challenge in transfusion safety.

Purpose:

  • To discuss the risks associated with blood transmission of unknown or uncommon infectious pathogens.
  • To highlight the importance of the precautionary principle in transfusion medicine.
  • To explore the factors influencing the consequences of such transmissions.

Summary:

  • While most post-transfusion infections stem from bacterial contamination or known pathogens, rare or unidentified infectious agents can also be transmitted.

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  • The impact of these transmissions varies based on the specific pathogen and the recipient's immune system.
  • This underscores the need for a cautious approach to blood product safety.

    • Impact:

    • Enhances understanding of transfusion-transmitted infections beyond common pathogens.
    • Informs policy and practice regarding blood donor screening and recipient safety.
    • Promotes a proactive stance on managing emerging infectious disease threats in transfusion medicine.