Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

cBlimp-1 expression in chick limb bud development.

Alice S Ha1, Robert D Riddle

  • 1Department of Cell and Developmental Biology, University of Pennsylvania School of Medicine, 1227 BRB II/III, Philadelphia, PA 19104, USA.

Gene Expression Patterns : GEP
|June 12, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

ACR Appropriateness Criteria® Chronic Knee Pain: Update 2026.

Journal of the American College of Radiology : JACR·2026
Same author

ACR Appropriateness Criteria® Chronic Ankle Pain: Update 2025.

Journal of the American College of Radiology : JACR·2026
Same author

ACR Appropriateness Criteria® Acute Shoulder Pain: 2024 Update.

Journal of the American College of Radiology : JACR·2025
Same author

ACR Appropriateness Criteria® Acute Elbow and Forearm Pain.

Journal of the American College of Radiology : JACR·2024
Same author

ACR Appropriateness Criteria® Chronic Elbow Pain.

Journal of the American College of Radiology : JACR·2022
Same author

ACR Appropriateness Criteria® Osteonecrosis: 2022 Update.

Journal of the American College of Radiology : JACR·2022
Same journal

Distinct cellular and subcellular distributions of the alpha and beta isoforms of Heat Shock Protein 90 in the mouse cerebral cortex.

Gene expression patterns : GEP·2026
Same journal

Molecular characterization and expression dynamics of Labeo rohita MDA5, its adaptor MAVS and pro-inflammatory cytokines against PAMPs stimulation and pathogen challenge.

Gene expression patterns : GEP·2026
Same journal

Defining the spatiotemporal expression pattern of Rap1 in the chicken embryonic spinal cord.

Gene expression patterns : GEP·2026
Same journal

Expression analysis of the TMC gene family in the auditory system during zebrafish embryonic development.

Gene expression patterns : GEP·2026
Same journal

Mapping the locations of barx1-expressing prechondrogenic condensation domains in the posterior arches during ceratobranchial cartilage formation in zebrafish.

Gene expression patterns : GEP·2026
Same journal

cDNA cloning, expression analysis, and subcellular localization of TRIM13 gene in zebrafish.

Gene expression patterns : GEP·2026
See all related articles

Researchers cloned the chick Blimp-1 (cBlimp-1) gene, a transcriptional repressor. cBlimp-1 is crucial for chick development, showing expression in limb buds, eyes, branchial arches, and otic placodes.

Area of Science:

  • Developmental Biology
  • Molecular Biology
  • Genetics

Background:

  • Blimp-1 is a conserved transcriptional repressor found in humans, mice, and frogs.
  • Understanding Blimp-1 homologs aids in deciphering conserved developmental pathways.

Purpose of the Study:

  • To clone the chick homolog of Blimp, designated cBlimp-1.
  • To determine the temporal and spatial expression pattern of cBlimp-1 during chick embryonic development.

Main Methods:

  • Gene cloning techniques were employed to isolate the cBlimp-1 gene.
  • Expression pattern analysis was performed during various stages of chick development.

Main Results:

  • The gene encoding the chick homolog of Blimp, cBlimp-1, was successfully cloned.

Related Experiment Videos

  • cBlimp-1 exhibits significant sequence identity with its known homologs.
  • cBlimp-1 expression was detected in specific embryonic structures including limb buds (apical ectodermal ridge and posterior dorsal ectoderm), developing eyes, branchial arches, and otic placodes.

    • Conclusions:

    • The cloning and expression analysis of cBlimp-1 provide insights into its role in chick embryogenesis.
    • The identified expression patterns suggest cBlimp-1 is involved in the development of key embryonic structures in chicks.