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Updated: Sep 25, 2026

Structured Exercise Regimen in Pulmonary Hypertension-Right Ventricular Failure in an Ovine Model
Published on: May 5, 2026
Nonpharmacologic treatment of resistant hypertensives by device-guided slow breathing exercises
Reuven Viskoper1, Irena Shapira, Rita Priluck
1WHO Collaborative Center for Prevention of CVD, the Barzilai Medical Center, Ashkelon, affiliated to the University of the Negev in Beer-Sheva, Ashkelon, Israel. reuvenv@barzi.health.gov.il
Background:
Recent studies have demonstrated the antihypertensive effect of slow breathing exercises, guided interactively by a device, in patients with uncontrolled blood pressure (BP) without changing medication. This study examined the response to the same treatment protocol in resistant hypertensives.
Methods:
Seventeen resistant hypertensives exercised device-guided slow breathing for 8 weeks, 15 min daily, and self-monitored BP. Data stored in the devices were collected on a PC-based system. Clinical outcomes were office and home BP changes from baseline to end values.
Results:
Significant reductions in both office BP (-12.9/-6.9 mm Hg, P <.001 and home BP (-6.4/-2.6 mm Hg, P <.01/P <.05) without side effects with 82% responders and good compliance.
Conclusions:
Resistant hypertensives can benefit from and are compliant with self-treatment by device-guided slow breathing.
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