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Auditory brainstem response in children with iron deficiency anemia
Hakan Cankaya1, Ahmet Faik Oner, Erol Egeli
1Department of Otolaryngology, Yüzüncü Yil University, Faculty of Medicine, Van, Turkey. hcankaya2@hotmail.com
Acta Paediatrica Taiwanica = Taiwan Er Ke Yi Xue Hui Za Zhi
|June 13, 2003
Summary
Iron deficiency anemia in children can impact auditory brainstem response (ABR) pathways. This study found prolonged ABR latencies, suggesting potential delays in auditory nerve and brainstem development due to insufficient iron.
Area of Science:
- Neuroscience
- Pediatrics
- Hematology
Background:
- Iron deficiency anemia (IDA) is a prevalent condition in children.
- Iron is crucial for neurological development, including myelination.
- Auditory brainstem response (ABR) assesses the integrity of the auditory pathway.
Purpose of the Study:
- To investigate the neurosensorial effects of IDA on auditory pathways in children.
- To evaluate auditory brainstem response (ABR) parameters in children with IDA compared to healthy controls.
Main Methods:
- Auditory brainstem response (ABR) was recorded in 33 children with IDA and 31 healthy children.
- Participants were categorized into three age groups (0-12, 13-36, 37-60 months).
- ABR parameters including latency, inter-peak latency, amplitude, and waveform were analyzed.
Main Results:
- Group I (12 months): Increased I-V interpeak latency in IDA children (p < 0.05).
- Group II (13-36 months): Increased Wave V latency and III-V interpeak latency in IDA children (p < 0.005).
- Group III (37-60 months): Increased Wave I latency in IDA children (p < 0.05).
Conclusions:
- IDA is associated with prolonged ABR latencies in children across different age groups.
- These findings suggest potential delays in myelination and/or iron-dependent enzyme function.
- IDA may adversely affect the maturation of the central auditory nervous system.