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The state of the immune system in thyroidectomized rats

G D Bendyug1, Yu A Grinevich, N N Khranovskaya

  • 1Institute of Oncology, Academy of Medical Sciences of Ukraine, Kiev. root@ucr.kiev.ua

Bulletin of Experimental Biology and Medicine
|June 13, 2003
PubMed

Disorders in the immune system manifesting in decreased weight and cellularity of lymphoid organs, decreased count of large granular lymphocytes, suppression of the immune response and metabolic activity of macrophages were observed in experimental animals 1-6 months after thyroidectomy. The intensity of these disorders depends on the period elapsed after the surgery. These disorders can result from not only changes in the levels of the pituitary-thyroid hormones, but also disturbances in the endocrine function of the thymus in thyroidectomized animals.

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