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Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
Published on: December 10, 2010
High-resolution 3D T2-weighted fast spin echo: new applications in the orbit
Erin M Simon1, Sharon McCaffery, Howard A Rowley
1Department of Radiology, University of California San Francisco, San Francisco, CA, USA. Simon@email.chop.edu
Neuroradiology
|June 13, 2003
Summary
A new MRI technique, 3D FSEz T2, enhances imaging of ocular masses. This advanced sequence improves diagnostic confidence and accuracy, potentially reducing the need for specialized equipment in ophthalmologic MR imaging.
Area of Science:
- Ophthalmology
- Radiology
- Medical Imaging
Background:
- Ophthalmologic Magnetic Resonance Imaging (MRI) benefits from high-resolution sequences.
- Standard 3D Fast Spin Echo T2 (3D FSE T2) sequences are available using head coils.
- Further resolution enhancement is possible through post-processing modifications.
Purpose of the Study:
- To describe the 3D FSEz T2 technique for ophthalmologic MRI.
- To report early clinical observations of 3D FSEz T2 in patients with ocular masses.
- To evaluate the impact of 3D FSEz T2 on diagnostic confidence and accuracy.
Main Methods:
- Utilized a modified 3D FSE T2 sequence incorporating zero-filled slice interpolation (3D FSEz T2).
- Applied the technique to standard MRI examinations in patients with ocular masses.
- Compared diagnostic information and confidence with conventional imaging series.
Main Results:
- The 3D FSEz T2 sequence altered the diagnosis in 41% (11/27) of studies, particularly for identifying treated retinoblastoma.
- Diagnostic confidence increased significantly in 38% (6/16) of remaining cases due to improved anatomical detail and lesion conspicuity.
- Interpretation remained unchanged in 10 cases.
Conclusions:
- The 3D FSEz T2 technique enhances diagnostic confidence in ophthalmologic MRI.
- This advanced sequence may obviate the need for dedicated surface coils.
- Improved spatial resolution aids in the diagnosis and characterization of ocular pathologies.
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