Related Experiment Video
Updated: Sep 25, 2026

Identification of OTX1 and OTX2 As Two Possible Molecular Markers for Sinonasal Carcinomas and Olfactory Neuroblastomas
Published on: February 28, 2019
Primary sinonasal non-Hodgkin's lymphoma masquerading as chronic rhinosinusitis: an issue of routine
Shih-Hung Chen1, Chuan-Song Wu, Kuang-Han Chan
1Department of Otorhinolaryngology, Taipei Municipal Chung-Hsin Hospital, Taiwan.
Abstract:
Primary non-Hodgkin's lymphoma (NHL) of the sinonasal tract is uncommon. Morphologically and radiographically, sinonasal lymphomas are difficult to distinguish from other malignant neoplasms or non-neoplastic processes. However, there is no general consensus about the need of routine histopathological examination for nasal polyps among otolaryngologists. We present a case of primary sinonasal NHL mimicking chronic rhinosinusitis and debate the issue of routine histopathological examination. We suggest that all tissues removed from the sinonasal tract during surgery must be submitted for histopathological examination. Failure to do so may miss diagnosis and delay appropriate treatment.
