Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

The classification of phocomelia.

G Tytherleigh-Strong1, G Hooper

  • 1Princess Margaret Rose Orthopaedic Hospital, Edinburgh, UK.

Journal of Hand Surgery (Edinburgh, Scotland)
|June 18, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Microscopic and macroscopic comparisons of 0.223 soft point and full metal jacket ammunition with bos taurus scapulae as a proxy to human flat bones.

BMJ military health·2020
Same author

Viability of <i>Bos taurus</i> scapulae as a flat bone proxy for ballistic testing.

BMJ military health·2020
Same author

Recurrent acromioclavicular joint dislocation with an associated coracoid fracture following acromioclavicular joint reconstruction.

Annals of the Royal College of Surgeons of England·2020
Same author

Ballistic gelatin calibration standardisation.

BMJ military health·2020
Same author

The Value of Routine Intravenous Tranexamic Acid in Total Hip Arthroplasty: A Preliminary Study.

Advances in orthopedics·2020
Same author

Prognostic impact of baseline tumour immune infiltrate on disease-free survival in patients with completely resected, BRAF<sup>v600</sup> mutation-positive melanoma receiving adjuvant vemurafenib.

Annals of oncology : official journal of the European Society for Medical Oncology·2020
Same journal

Dorsal (AO/ASIF) pi-plate osteosynthesis in the treatment of distal intraarticular radius fractures.

Journal of hand surgery (Edinburgh, Scotland)·2006
Same journal

Brachial plexus injury in snowboarding.

Journal of hand surgery (Edinburgh, Scotland)·2006
Same journal

Septic arthritis of the small joints of the hand.

Journal of hand surgery (Edinburgh, Scotland)·2006
Same journal

Problematic bone fixation with pyrocarbon implants in proximal interphalangeal joint replacement: short-term results.

Journal of hand surgery (Edinburgh, Scotland)·2006
Same journal

A leiomyoma arising from the deep palmar arterial arch.

Journal of hand surgery (Edinburgh, Scotland)·2006
Same journal

Local anaesthesia for carpal tunnel decompression: a comparison of two techniques.

Journal of hand surgery (Edinburgh, Scotland)·2006
See all related articles

Phocomelia, a rare limb malformation, was studied in 24 patients. Many cases did not fit existing classification systems, suggesting phocomelia is not an intercalary defect.

Area of Science:

  • Orthopedics
  • Developmental Biology
  • Clinical Genetics

Background:

  • Phocomelia is a rare congenital limb malformation.
  • Existing classification systems for limb defects may not encompass all phocomelic presentations.

Purpose of the Study:

  • To analyze the characteristics of phocomelic upper limbs.
  • To evaluate the applicability of the Frantz and O'Rahilly classification system to these cases.
  • To determine the nature of phocomelia as a developmental defect.

Main Methods:

  • Retrospective analysis of 24 patients with 44 phocomelic upper limbs.
  • Classification of limbs using the Frantz and O'Rahilly system.
  • Detailed characterization of limbs that did not fit the classification.

Related Experiment Videos

Main Results:

  • Only 11 out of 44 limbs (25%) could be classified using the Frantz and O'Rahilly system.
  • Significant variability and unique characteristics were observed in the non-classifiable limbs.
  • Findings support that phocomelia represents a distinct type of limb malformation, not an intercalary defect.

Conclusions:

  • The Frantz and O'Rahilly classification system has limited utility for all phocomelic upper limb presentations.
  • Phocomelia exhibits diverse morphological features not fully captured by current classifications.
  • Phocomelia is confirmed to be a non-intercalary developmental anomaly of the upper limb.