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Published on: October 12, 2017
[Intermittent bladder-ureteral reflux in children]
Insights
This study identifies causes of intermittent vesicoureteral reflux (IVR) in children, correlating them with anatomical changes and bladder inflammation. It proposes a diagnostic algorithm and tailored treatments to preserve kidney function.
Area of Science:
- Pediatric Urology
- Nephrology
Context:
- Intermittent vesicoureteral reflux (IVR) is a condition affecting children.
- Understanding the underlying causes and anatomical factors is crucial for effective management.
Purpose:
- To investigate the causes of IVR in children.
- To correlate IVR with vesicoureteral anastomosis changes and bladder inflammation.
- To develop a diagnostic algorithm and therapeutic strategies for IVR.
Summary:
- A combined clinical and laboratory examination of 193 children with IVR was conducted.
- The study analyzed the role of gas cystography in IVR diagnosis.
- Treatment policies were based on kidney function and IVR etiology, with analysis of short- and long-term outcomes.
Impact:
- The study provides a diagnostic algorithm for IVR detection.
- It outlines therapeutic approaches to preserve and improve renal function in affected children.
- Methods for IVR prophylaxis are suggested to prevent long-term renal damage.
Abstract:
Basing on the results of a combined clinical and laboratory examination of 193 children treated in the Research Institute of Urology in 1992-1999, the authors studied causes underlying intermittent vesicoureteral reflux (IVR) in correlation with anatomo-functional changes in vesicoureteral anastomosis and severity of inflammation in the urinary bladder. They suggest a diagnostic algorithm of detecting IVR with assessment of gas cystography role in the diagnosis; give definition of IVR; describe therapeutic policy in accordance with functional state of the affected kidney and cause of IVR onset; analyse short- (6-12 months) and long-term (12-36 months) treatment results; outline methods of IVR prophylaxis to save and improve renal function.
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