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[Bone metabolism in men].

Maurice Audran1, Paolo Insalaco, Erick Legrand

  • 1Service de Rhumatologie, CHU d'Angers, INSERM EMI 0335-LHEA, Faculté de Médecine, Angers, France. MaAudran@chu-angers.fr

Progres En Urologie : Journal De L'Association Francaise D'Urologie Et De La Societe Francaise D'Urologie
|June 21, 2003
PubMed
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This review explores male bone metabolism, detailing cellular functions and hormonal impacts. Recent findings suggest estrogens, not just androgens, significantly influence bone health in men.

Area of Science:

  • Endocrinology
  • Bone Biology
  • Physiology

Context:

  • Bone metabolism is crucial for skeletal health.
  • Hormonal regulation significantly impacts bone density and integrity.
  • Understanding male bone physiology is essential for clinical applications.

Purpose:

  • To review the primary physiological aspects of bone metabolism in males.
  • To describe the functions of bone cells and their roles.
  • To elucidate the hormonal influences on male bone biology.

Summary:

  • This paper details the cellular components and functions within bone tissue.
  • It examines the hormonal factors affecting bone metabolism, including androgens.
  • Emerging evidence highlights a potentially dominant role for estrogens in regulating male bone health, challenging traditional views.

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Impact:

  • Provides a comprehensive overview of male bone metabolism for researchers and clinicians.
  • Highlights the evolving understanding of hormonal roles, particularly estrogens, in male skeletal health.
  • Contributes to the knowledge base for developing targeted therapies for bone diseases in men.