[Modeling viability of mammalian cells exposed to ionizing radiation with different linear energy transfer]
Related Experiment Video
Updated: Sep 25, 2026

06:51
Dosimetry for Cell Irradiation using Orthovoltage (40-300 kV) X-Ray Facilities
Published on: February 20, 2021
1Joint Institute for Nuclear Research, ul. Joliot-Curie 6, Dubna, Moscow Region, 141980 Russia.
Biofizika
|June 21, 2003
Abstract:
A mathematical model of the survival of mammalian cells exposed to ionizing radiation is proposed, which takes into account nonuniform radiosensitivity of different regions of DNA. The model is based on the assumption that the double-strand breaks of the anchor DNA, induced either directly by irradiation or by enzymes, play a key role in the lethal radiation effect. The model survival curves are in good agreement with experimental curves measured in different laboratories.

