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Related Experiment Videos

Culture-based group B streptococcal screening. Adherence to current guidelines.

Michael G Pinette1, Joseph R Wax, Jacquelyn Blackstone

  • 1Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Maine Medical Center, Portland, ME 04102, USA. cartia@mmc.org

The Journal of Reproductive Medicine
|June 21, 2003
PubMed
Summary

Universal screening effectively identifies women needing intrapartum antibiotics for group B Streptococcus (GBS). Most GBS-positive mothers received timely antibiotics, though some cases were missed due to rapid labor or errors.

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Area of Science:

  • Obstetrics and Gynecology
  • Infectious Disease Prevention
  • Maternal Health

Background:

  • Group B Streptococcus (GBS) poses a significant risk during childbirth.
  • Intrapartum antibiotics are crucial for preventing neonatal GBS transmission.
  • Universal screening strategies aim to optimize antibiotic prophylaxis.

Purpose of the Study:

  • To evaluate the effectiveness of universal screening for identifying and treating GBS-positive women with intrapartum antibiotics.
  • To assess the rate of appropriate antibiotic administration in GBS-positive pregnant individuals.

Main Methods:

  • Retrospective chart review of patients delivering at or after 36 weeks gestation.
  • Analysis of GBS culture results, antibiotic orders, and timing relative to delivery.

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  • Inclusion/exclusion criteria applied to assess chemoprophylaxis efficacy.

    • Main Results:

    • GBS screening results were available for approximately 95% of eligible patients.
    • 84% of GBS-positive patients received appropriate chemoprophylaxis, increasing to 94% after excluding elective cesareans.
    • Ideal antibiotic prophylaxis (≥2 hours prior to delivery) was achieved in 87% of cases.

    Conclusions:

    • Universal GBS culturing and intrapartum antibiotic prophylaxis are largely achievable.
    • A small percentage of GBS-positive women (6%) did not receive treatment.
    • Suboptimal prophylaxis (13%) resulted from factors like rapid labor and administrative errors.