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Usefulness of turbo-fluid-attenuated inversion-reovery (tFLAIR) sequence in diagnosing meningioma
Teruhiko Shimizu1, Hitoshi Miki, Takashi Takeguchi
1Department of Radiology, Ehime University School of Medicine Onsen-gun, Japan.
Purpose:
We evaluated qualitatively and quantitatively the usefulness of turbo-FLAIR (tFLAIR) in diagnosing meningioma in comparison with the T2-weighted turbo spin echo (T2W-TSE) sequence.
Materials And Methods:
Forty-eight patients diagnosed with meningioma were studied. In the qualitative study, we evaluated tumor delineation, contrast (Co) of tumor-to-CSF (cerebrospinal fluid), Co of tumor-to-brain parenchyma, Co of peripheral edema-to-brain parenchyma, and detectability of tumor margin. In quantitative study-1, using signal intensity (SI), we measured SI and calculated Co-SI of tumor-to-gray matter, Co-SI of tumor-to-white matter, Co-SI of peripheral edema-to-white matter, and Co-SI of tumor-to-CSF. In quantitative study-2, using film density, we measured density (De) on hard-copy film images and calculated Co-De for the same items as in quantitative study-1.
Results:
In the qualitative study, tFLAIR was superior to T2W-TSE in tumor delineation, Co of tumor-to-CSF, Co of tumor-to-brain parenchyma, and Co of peripheral edema-to-brain parenchyma. In quantitative study-1, tFLAIR was superior to T2W-TSE in Co-SI of tumor-to-CSF, however, T2W-TSE was superior to tFLAIR in Co-SI of tumor-to-white matter. In quantitative study-2, tFLAIR was superior to T2W-TSE in all Co-De.
Conclusion:
tFLAIR was superior to T2W-TSE in the depiction of meningioma.