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Updated: Sep 25, 2026

Repair of a Critical-sized Calvarial Defect Model Using Adipose-derived Stromal Cells Harvested from Lipoaspirate
Published on: October 31, 2012
Reconstruction of the frontal calvarian continuity in a child using a freeze-preserved autogenous bone graft
Jan-Hendrik Lenz1, Kai-Olaf Henkel, Volker Hingst
1Department of Oral and Maxillofacial Plastic Surgery, Medical School, Rostock University, Rostock, Germany.
Abstract:
Today, extended craniofacial defects in childhood can be treated by using modern techniques of bone banking and osteosynthesis, of particular importance when the restoration needs to consider calvarial growth. This is a report of an 8-year-old boy whose right frontal bone was removed during primary multidisciplinary trauma care. The bone was stored at a tissue bank using sterilization and freeze-dried preservation. Nine months later the graft was replaced and fixed with resorbable miniplates. Postoperatively no complications were observed and the (auto)graft has taken well. There was symmetrical craniofacial growth as well as a good aesthetic result three years after reconstruction.
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