Related Experiment Videos
Yersinia pestis TonB: role in iron, heme, and hemoprotein utilization
Robert D Perry1, Jessica Shah, Scott W Bearden
1Department of Microbiology, Immunology, and Molecular Genetics, University of Kentucky, Lexington, Kentucky 40536-8994, USA. rperry@pop.uky.edu
Infection and Immunity
|June 24, 2003
Abstract:
In Yersinia pestis, the siderophore-dependent yersiniabactin (Ybt) iron transport system and heme transport system (Hmu) have putative TonB-dependent outer membrane receptors. Here we demonstrate that hemin uptake and iron utilization from Ybt are TonB dependent. However, the Yfe iron and manganese transport system does not require TonB.