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Hypertension and renal dysfunction: NHANES III.

Camille A Jones1

  • 1Boston, MA, USA. bmcclellan@gmcf.org

Journal of the American Society of Nephrology : JASN
|June 24, 2003
PubMed
Summary

Hypertension and diabetes are increasing end-stage renal disease (ESRD) incidence globally. Data from the United States on hypertension

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Area of Science:

  • Nephrology
  • Public Health
  • Epidemiology

Background:

  • End-stage renal disease (ESRD) incidence is rising globally, driven by diabetes and hypertension.
  • While diabetes is the primary cause of ESRD in Singapore, hypertension prevalence is rapidly increasing.
  • Hypertension-related renal complications may become more prevalent in Singapore's future population.

Purpose of the Study:

  • To compare hypertension prevalence in the US and Singapore.
  • To analyze the association between hypertension and renal dysfunction in the US.
  • To inform the development of a renal disease prevention program in Singapore.

Main Methods:

  • Review of published and unpublished data presented at a conference.
  • Comparison of recent hypertension prevalence data from the United States and Singapore.
  • Analysis of the association between hypertension and serum creatinine, urinary albumin excretion, and ESRD in the United States.

Main Results:

  • The United States and Singapore show increasing trends in end-stage renal disease (ESRD) incidence.
  • Diabetes is a leading cause of ESRD in both countries, with rapidly rising hypertension prevalence in Singapore.
  • US data demonstrate associations between hypertension, elevated serum creatinine, increased urinary albumin excretion, and ESRD.

Conclusions:

  • Hypertension is a significant and growing risk factor for ESRD globally.
  • US data on hypertension's renal impact can inform Singapore's renal disease prevention strategies.
  • Comprehensive prevention programs are crucial to address rising ESRD rates linked to hypertension and diabetes.

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