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Comparative sequence analysis and predictions for the envelope glycoproteins of insect endogenous retroviruses
Yolande Misseri1, Gilles Labesse, Alain Bucheton
1Institut de Génétique Humaine, 141 rue de la cardonille, F-34396 Montpellier Cedex 5, France.
Trends in Microbiology
|June 26, 2003
Abstract:
Insect endogenous retroviruses (IERVs) are present in the genome of several species. Previous studies have shown a relationship between the envelope glycoproteins (Envs) and fusion proteins (FPs) of several baculoviruses. We used this sequence similarity to predict fusion domains in the Envs of IERVs. We suggest that FPs and Envs share several specific sequence and structural motifs with other RNA viruses in the viral transmembrane protein superfamily.