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Dihydrofolate reductase mutant with exceptional resistance to methotrexate but not to trimetrexate

Pamela Pineda1, Aaron Kanter, R Scott McIvor

  • 1Departments of Medicinal Chemistry and of Genetics and Development, University of Minnesota, Minneapolis, Minnesota 55455, USA.

Journal of Medicinal Chemistry
|June 27, 2003
PubMed

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