Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Introduction to force01:25

Introduction to force

Consider water flowing from a nozzle to a turbine vane. As the water hits the turbine vane, it exerts a force that causes it to move along the flow of direction. Force is an impact that changes an object's motion, shape, or orientation. Forces can be caused by physical contact, such as a push or pull, or through non-contact interactions, such as magnetic or gravitational forces. Force is a vector quantity with both magnitude and direction, and is measured in newtons (N) in the SI unit system.
An Introduction to Mechanics01:28

An Introduction to Mechanics

Humans have been making ships, shelters, pyramids, weapons, agricultural equipment, and many more items without recording the process or theory behind them for centuries. It would be challenging to document the evolution of mechanics from its origin to the present.
According to records, the history of mechanics starts with Aristotle (384–322 BC). He related mechanics to physical theory, aiming for a universal synthesis.
Newton defined mechanics as the branch of physical science that studies the...
Introduction to Statistics01:17

Introduction to Statistics

The science of statistics involves collecting, analyzing, interpreting, and presenting data. The method of collecting, organizing, and summarizing data is called descriptive statistics. The systematic method of drawing inferences from the sample data and predicting unknown characteristics of a population is called inferential statistics.
In statistics, the collection of individuals or objects under study is called population. The idea of sampling is to select a portion of the larger population...
Newton's First Law: Introduction01:17

Newton's First Law: Introduction

Motion draws our attention. Motion itself can be beautiful, causing us to marvel at the forces needed to create spectacular sights, such as that of a dolphin jumping out of the water, the flight of a bird, or the orbit of a satellite. The study of motion is kinematics, but kinematics only describes the way objects move—their velocity and acceleration. Dynamics considers the forces that affect the motion of moving objects and systems. Newton's laws of motion are the foundation of dynamics. These...
Chromatography: Introduction01:10

Chromatography: Introduction

Chromatography is a technique used to separate compounds based on differences of partitioning between two phases, the stationary phase and the mobile phase.
The phase in which the compounds linger or on which the compounds adsorb is called the stationary phase, whereas the mobile phase is the solvent that carries the solutes to be analyzed. In traditional column chromatography, the mixture flows through the stationary phase, and the compounds partition between the stationary and mobile phases...
Biostatistics: Overview01:20

Biostatistics: Overview

Biostatistics plays a crucial role in understanding and analyzing data in healthcare and biology. Biostatisticians conduct experiments, gather evidence, and draw meaningful conclusions using statistical methods and techniques. Different variables form the foundation of biostatistical analysis, allowing researchers to understand and interpret data effectively. These variables are classified into different types, each serving a specific purpose in statistical analysis.
Discrete variables are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SonoPIN enables precise, noninvasive, and efficient intracellular delivery of PROTACs.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Coordination of cell organelles to promote metabolon formation.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Structural insights into the exchange mechanism of a replicative DNA polymerase.

Nucleic acids research·2025
Same author

Multiplex mapping of protein-protein interaction interfaces.

Proceedings of the National Academy of Sciences of the United States of America·2025
Same author

Adaptive nuclear GTP synthesis promotes glioblastoma treatment resistance and is a targetable vulnerability in patients.

medRxiv : the preprint server for health sciences·2025
Same author

The bacteriophage T4 replisome: a model system for understanding DNA replication mechanisms.

EcoSal Plus·2025
Same journal

Mammalian Respiratory Chain Complex Assemblies and Their Links to Mitochondria Stress-Induced Human Diseases.

Advances in experimental medicine and biology·2026
Same journal

Enzyme Assemblies in Nucleotide Metabolism: Structure, Regulation, and Disease Implications.

Advances in experimental medicine and biology·2026
Same journal

The Pyruvate Dehydrogenase Complex: A 90-Year-Old Enigma Shaping the Future of Structural Enzymology.

Advances in experimental medicine and biology·2026
Same journal

Regulation of the Anti-termination RNA Transcription Complex by Lon-Mediated Lambda N Degradation.

Advances in experimental medicine and biology·2026
Same journal

PCNA Macromolecular Complexes: PCNA Serves as a Molecular Hub Regulating Multiple Cellular Processes Inside and Outside of the Nucleus.

Advances in experimental medicine and biology·2026
Same journal

Dynamic Assemblies in Genome Maintenance.

Advances in experimental medicine and biology·2026
See all related articles

Related Experiment Video

Updated: Jun 24, 2026

Micro-scale Engineering for Cell Biology
04:42

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

Introduction.

Stephen J Benkovic1

  • 1Department of Chemistry, The Pennsylvania State University, University Park, PA, USA. sjb1@psu.edu.

Advances in Experimental Medicine and Biology
|June 23, 2026
PubMed
Summary
This summary is machine-generated.

This essay traces the evolution of enzymatic catalysis research, from early bioorganic models to current multienzyme complex studies. It provides historical context and future perspectives for the volume

Area of Science:

  • Biochemistry
  • Enzymology
  • Chemical Biology

Background:

  • The field of enzymatic catalysis has evolved significantly over decades.
Keywords:
Bioorganic chemistryEnzyme compartmentalizationEnzymologyMetabolonsMulti-enzyme complexesPurinosomeReplisome

Related Experiment Videos

Last Updated: Jun 24, 2026

Micro-scale Engineering for Cell Biology
04:42

Micro-scale Engineering for Cell Biology

Published on: October 1, 2007

  • Early research focused on bioorganic models and physical organic studies of enzyme mechanisms.
  • Progress has led to the investigation of complex enzymatic systems.