Emerging HIV-1 epidemic in China in men who have sex with men

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Specific Marking of HIV-1 Positive Cells using a Rev-dependent Lentiviral Vector Expressing the Green Fluorescent Protein
09:53

Specific Marking of HIV-1 Positive Cells using a Rev-dependent Lentiviral Vector Expressing the Green Fluorescent Protein

Published on: September 23, 2010

Kyung-Hee Choi1, Hui Liu, Yaqi Guo

  • 1Center for AIDS Prevention Studies, University of California, San Francisco, CA 9410, USA. khchoi@psg.ucsf.edu

Lancet (London, England)
|June 27, 2003
PubMed

Insights

A study in Beijing found 3.1% of men who have sex with men were infected with human immunodeficiency virus type 1 (HIV-1). Older age and numerous sexual partners were linked to higher HIV-1 risk.

Area of Science:

  • Epidemiology
  • Public Health
  • Infectious Diseases

Background:

  • China faces a significant human immunodeficiency virus type 1 (HIV-1) epidemic.
  • Limited data exists on HIV-1 prevalence and risk factors among men who have sex with men (MSM) in China.

Purpose of the Study:

  • To determine the seroprevalence of HIV-1 infection in MSM in Beijing.
  • To identify risk factors associated with HIV-1 seropositivity in this population.

Main Methods:

  • A cross-sectional study was conducted among 481 MSM in Beijing.
  • HIV-1 serostatus was assessed, and participants completed questionnaires on sexual behaviors and demographics.

Main Results:

  • HIV-1 seroprevalence was 3.1% (15 out of 481 men).
  • Unprotected anal intercourse was reported by 49% of participants in the preceding 6 months.
  • HIV-1 seropositivity was independently associated with age over 39 years and having had more than 20 male sexual partners.

Conclusions:

  • The findings indicate a notable HIV-1 prevalence among MSM in Beijing.
  • The study highlights potential for HIV-1 transmission within the MSM community and to heterosexual partners.

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