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Gene therapy in the treatment of intestinal inflammation
Catherine van Montfrans1, Anje A te Velde, Sander J H van Deventer
1Department of Experimental Internal Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands.
International Journal of Colorectal Disease
|June 27, 2003
Background:
Local expression of anti-inflammatory or immunoregulatory genes may offer an alternative treatment of gastrointestinal inflammation.
Discussion:
We review the basic requirements for gene therapy, the possible routes of delivery, and the different strategies for specific targeting focusing on gastrointestinal inflammation.