Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Genome comparisons and analysis.

Samuel Karlin1, Jan Mrázek, Andrew J Gentles

  • 1Department of Mathematics, Stanford University, Stanford, CA 94305, USA. karlin@math.stanford.edu

Current Opinion in Structural Biology
|July 2, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

DeSpotX: Identifiability-Based Decontamination for Spatial Transcriptomics.

bioRxiv : the preprint server for biology·2026
Same author

Non-invasive profiling of the tumour microenvironment with spatial ecotypes.

Nature·2026
Same author

Correction: A Helicobacter pylori flagellar motor accessory is needed to maintain the barrier function of the outer membrane during flagellar rotation.

PLoS pathogens·2026
Same author

Lymph node colonization induces tissue remodeling via immunosuppressive fibroblast-myeloid cell niches supporting metastatic tolerance.

Cancer cell·2026
Same author

PRECOG update: an augmented resource of clinical outcome associations with gene expression for adult, pediatric, and immunotherapy cohorts.

Nucleic acids research·2025
Same author

The Immune Microenvironment of Transplant Glomerulitis.

Kidney international reports·2025
Same journal

Metabolic disruptions through a three-dimensional genomic lens.

Current opinion in structural biology·2026
Same journal

Collective variable design for biomolecular conformational dynamics.

Current opinion in structural biology·2026
Same journal

Polymer scaling in protein crowding: From dilute coils to semidilute meshes.

Current opinion in structural biology·2026
Same journal

Tuning the physicochemical properties of rationally designed protein-based biomolecular condensates.

Current opinion in structural biology·2026
Same journal

Editorial overview: Folding, binding and protein design.

Current opinion in structural biology·2026
Same journal

Macromolecular crowding reshapes the conformational landscapes of intrinsically disordered proteins: mechanisms, cellular contexts, and functional consequences.

Current opinion in structural biology·2026
See all related articles

The post-genomic era expands cellular process understanding through new techniques like RNA interference and comparative genomics. Future research focuses on integrating vast biological data for systems-level insights.

Area of Science:

  • Genomics and Molecular Biology
  • Bioinformatics

Background:

  • The post-genomic era is characterized by rapid genome sequencing and advanced molecular analysis tools.
  • Understanding complex cellular processes requires integrating diverse biological data.

Purpose of the Study:

  • To highlight recent advancements in dissecting cellular processes at the molecular level.
  • To emphasize the growing importance of data integration in biological research.

Main Methods:

  • Application of RNA interference for gene function characterization in eukaryotes.
  • Comparative genomic analysis, specifically between human and mouse genomes.
  • Development of methods for resolving conflicting phylogenetic data.

Main Results:

Related Experiment Videos

  • RNA interference effectively characterizes gene loss-of-function phenotypes.
  • Comparative genomics provides insights into evolutionary relationships.
  • New methods improve the accuracy of phylogenetic reconstructions.
  • Advancements contribute to enriched biological databases like COG.

Conclusions:

  • The field is rapidly advancing in molecular-level cellular process dissection.
  • Integrating large-scale biological data is crucial for future discoveries.
  • The post-genomic era necessitates a systems biology approach.