PGC-1alpha at the crossroads of type 2 diabetes

Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice.

Nature aging·2026

Pancreatic islet α cell function and proliferation require the arginine transporter SLC7A2.

The Journal of clinical investigation·2026

Proinsulin regulators identified with CRISPR screen and in vivo mouse QTL mapping.

Nature communications·2026

Distinct genetic architecture of gene and isoform level QTL in the Diversity Outbred (DO) mouse population.

bioRxiv : the preprint server for biology·2026

Restriction of Individual Branched-Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2026

A structural model of toxic amyloid oligomers involved in type 2 diabetes.

Proceedings of the National Academy of Sciences of the United States of America·2026

Toward the clinical application of long-read sequencing in repeat-expansion disorders.

Nature genetics·2026

Distinguishing different psychiatric disorders using DDx-PRS.

Nature genetics·2026

Adaptive evolution of polyploid crops.

Nature genetics·2026

Rare variant effect estimation and polygenic risk prediction.

Nature genetics·2026

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

Nature genetics·2026

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Nature genetics·2026

Design, synthesis and antitubercular evaluation of novel 5,6-diphenyl-1,2,4-triazine-piperazine derivatives targeting mycobacterial dihydrofolate reductase.

ADMET & DMPK·2026

Declared Inactive Ingredients in US Oral Drug Listings: A Reproducible Census of Prevalence, Labeling Coverage, and Within-Name Variation.

Cureus·2026

Disease-Modifying Antirheumatic Drugs for Hand Osteoarthritis: A Systematic Review and Network Meta-analysis.

Hand surgery & rehabilitation·2026

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics.

Epilepsia open·2026

Phenotype-Dependent Effect of Bedtime Antihypertensive Dosing on Nocturnal Blood Pressure: A Meta-Analysis Guided by Non-Dipper Prevalence.

Journal of clinical hypertension (Greenwich, Conn.)·2026

Sex Hormones in Psoriatic Disease: A Systematic Review.

American journal of clinical dermatology·2026

Related Experiment Videos

PGC-1alpha at the crossroads of type 2 diabetes

Related Concept Videos

Lifelong restriction of dietary valine has sex-specific benefits for health and lifespan in mice.

Pancreatic islet α cell function and proliferation require the arginine transporter SLC7A2.

Proinsulin regulators identified with CRISPR screen and in vivo mouse QTL mapping.

Distinct genetic architecture of gene and isoform level QTL in the Diversity Outbred (DO) mouse population.

Restriction of Individual Branched-Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice.

A structural model of toxic amyloid oligomers involved in type 2 diabetes.

Toward the clinical application of long-read sequencing in repeat-expansion disorders.

Distinguishing different psychiatric disorders using DDx-PRS.

Adaptive evolution of polyploid crops.

Rare variant effect estimation and polygenic risk prediction.

Spatial analysis of head and neck cancer identifies two ecosystems with distinct modes of epithelial-to-mesenchymal transition.

PLCG2 downregulation impairs synaptic function and increases Alzheimer's disease hallmarks in neuronal cultures.

Design, synthesis and antitubercular evaluation of novel 5,6-diphenyl-1,2,4-triazine-piperazine derivatives targeting mycobacterial dihydrofolate reductase.

Declared Inactive Ingredients in US Oral Drug Listings: A Reproducible Census of Prevalence, Labeling Coverage, and Within-Name Variation.

Disease-Modifying Antirheumatic Drugs for Hand Osteoarthritis: A Systematic Review and Network Meta-analysis.

Efficacy and safety of fenfluramine in Dravet syndrome: The impact of patient clinical characteristics.

Phenotype-Dependent Effect of Bedtime Antihypertensive Dosing on Nocturnal Blood Pressure: A Meta-Analysis Guided by Non-Dipper Prevalence.

Sex Hormones in Psoriatic Disease: A Systematic Review.

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PGC-1alpha at the crossroads of type 2 diabetes

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