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[Hansenula anomala fungemia]

S C Mestroni1, A J Bava

  • 1Laboratorio de Micología, Hospital Interzonal General de Agudos (HIGA) San Martín, Cátedra de Micología y Parasitología, Facultad de Ciencias Exactas, Universidad Nacional de La Plata, La Plata, Argentina. nemes@netverk.com.ar

Revista Argentina De Microbiologia
|July 2, 2003
PubMed

Insights

Hansenula anomala (Candida pelliculosa) caused five fungemia episodes in hospitalized patients. This yeast is an emerging pathogen, particularly in immunocompromised individuals, necessitating increased clinical awareness.

Area of Science:

  • Medical Mycology
  • Infectious Diseases
  • Clinical Microbiology

Context:

  • Reports five episodes of fungemia caused by Hansenula anomala (Candida pelliculosa) in a single hospital over 13 months.
  • Identifies risk factors including antibiotic/corticoid use, catheters, surgery, and prematurity.
  • Highlights the potential for nosocomial outbreaks due to simultaneous cases in different wards.

Purpose:

  • To report and characterize fungemia episodes caused by Hansenula anomala.
  • To assess the clinical significance and predisposing factors associated with H. anomala fungemia.
  • To raise awareness of H. anomala as an emergent fungal pathogen in clinical settings.

Summary:

  • Five fungemia cases were identified in four adults and one preterm infant.
  • Blood cultures processed via BacTAlert and lysis-centrifugation, with API 32 C for identification.
  • Two of five patients died despite antifungal treatment, suggesting high-risk patient populations.

Impact:

  • Suggests Hansenula anomala is an emerging fungal pathogen causing fungemia.
  • Emphasizes the need to consider H. anomala in patients with predisposing factors.
  • Highlights the potential for hospital-acquired outbreaks of this yeast infection.

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