Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Patch-test-induced subjective complaints.

W G Kamphof1, L Kunkeler, S C E Bikkers

  • 1Department of Occupational Dermatology, Free University Medical Center, Amsterdam, The Netherlands.

Dermatology (Basel, Switzerland)
|July 2, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Diurnal volume changes of the lower legs in healthy males with a profession that requires standing.

Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)·2016
Same author

Low-molecular-weight heparin added to aspirin in the prevention of recurrent early-onset pre-eclampsia in women with inheritable thrombophilia: the FRUIT-RCT.

Journal of thrombosis and haemostasis : JTH·2011
Same author

Skin diseases in Europe. Prevention and rehabilitation.

European journal of dermatology : EJD·2009
Same author

Routine patch testing with the preservative system Kathon CG.

International journal of cosmetic science·2009
Same author

Letter to the editor.

International journal of cosmetic science·2009
Same author

Contact dermatitis due to Paeonia (peony): a rare sensitizer?

Contact dermatitis·2009
Same journal

Survey on Difficult to Treat Tinea: A Sub-Saharan Africa Snapshot.

Dermatology (Basel, Switzerland)·2026
Same journal

Mpox Outbreaks Beyond Historically Endemic Regions: A Clinical Review of Vaccination Strategies and Public Health Challenges.

Dermatology (Basel, Switzerland)·2026
Same journal

Clinical Insights and Prognostic Factors in Frontal Fibrosing Alopecia and Lichen Planopilaris: A Retrospective Cohort Study.

Dermatology (Basel, Switzerland)·2026
Same journal

Descriptive Analysis of DRESS Reports from EudraVigilance and DRESS Cases from the RegiSCAR-project.

Dermatology (Basel, Switzerland)·2026
Same journal

The Role of the Vagus Nerve and Its Stimulation in Modulating Inflammatory Skin Diseases and Other Dermatologic Conditions: From Mechanisms to Therapeutics.

Dermatology (Basel, Switzerland)·2026
Same journal

Skin Barrier Dysfunction, Antimicrobial Peptide Alterations, and Microbiome Changes in Solid Cancer Patients Treated with Epidermal Growth Factor Receptor Inhibitors.

Dermatology (Basel, Switzerland)·2026
See all related articles

Epicutaneous patch testing can cause subjective complaints like tiredness and shakiness, particularly when positive reactions are present. This study confirms a link between patch tests and patient discomfort.

Area of Science:

  • Dermatology
  • Allergology
  • Clinical Immunology

Background:

  • Patients undergoing epicutaneous patch testing frequently report subjective complaints.
  • Understanding these complaints is crucial for accurate diagnostic interpretation.

Purpose of the Study:

  • To investigate the association between the patch testing procedure and subjective patient complaints.
  • To determine if patch test reactions correlate with reported symptoms.

Main Methods:

  • A prospective study of 102 consecutive patients undergoing patch testing.
  • Patients completed forms detailing subjective complaints (e.g., tiredness, shakiness) on specific days post-application.
  • Inclusion criteria required patients to be asymptomatic on the day of patch application.

Related Experiment Videos

Main Results:

  • A significant number of patients experienced complaints on days 2 and 3 post-testing (17/102), exceeding chance expectations (p<0.01).
  • A positive correlation was observed between the number of positive patch test reactions and the severity of complaints on days 2 and 3 (r=0.19 and r=0.15, respectively; p<0.001).
  • Patients reporting shakiness had a significantly higher proportion of positive patch tests (72.2%; p<0.05).

Conclusions:

  • Patch testing can induce subjective complaints in patients.
  • The presence of positive patch test reactions is associated with increased patient discomfort.