Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Immunological synapses and neuronal synapses].

Alain Trautmann1, Patrick Revy, Emmanuel Donnadieu

  • 1Département de Biologie Cellulaire, Institut Cochin, Inserm U.567, Cnrs UMR 8104, 22, rue Méchain, 75014 Paris, France. trautmann@cochin.inserm.fr

Medecine Sciences : M/S
|July 3, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An ex vivo assay to assess CAR T cell cytotoxicity in viable tumor tissues using a two-step staining protocol.

Methods in cell biology·2026
Same author

Ribosomal RNA processing impairments in a B cell immunodeficient patient with WDR75 variants.

Journal of human immunity·2026
Same author

Genetic aspects of telomere biology disorders.

Seminars in hematology·2026
Same author

[Towards in vivo production of CAR-T cells: an announced revolution?]

Medecine sciences : M/S·2026
Same author

Functional impact of the eIF6 N106S mutation on ribosome biogenesis in wild type and Shwachman-Diamond syndrome cells.

Molecular medicine (Cambridge, Mass.)·2026
Same author

An in vivo CRISPR screen unveils promising target genes to improve CAR-T cell efficacy in a solid tumor model.

Molecular therapy : the journal of the American Society of Gene Therapy·2026
Same journal

[CREPT: An ally of immunotherapy for the fight against non-small-cell lung cancers].

Medecine sciences : M/S·2026
Same journal

[A new regulatory mechanism of HIF-1α: the ROS-ATM-CHK2 axis at the core of tumor angiogenesis].

Medecine sciences : M/S·2026
Same journal

[Vibrio-host interactions: from the environmental niche to virulence].

Medecine sciences : M/S·2026
Same journal

[RcsF, hyperconnected sentinel of the bacterial envelope].

Medecine sciences : M/S·2026
Same journal

[Single-cell RNA-sequencing: shattering the clone myth].

Medecine sciences : M/S·2026
Same journal

[No, Physarum blobs do not have 720 sexes!]

Medecine sciences : M/S·2026
See all related articles

The immunological synapse forms between immune cells like T lymphocytes and antigen-presenting cells. This review details synapse structure, function, and communication parallels with nervous system synapses.

Area of Science:

  • Immunology
  • Cell Biology
  • Neuroscience

Context:

  • The immunological synapse is a critical interface between T lymphocytes and antigen-presenting cells.
  • Understanding synapse structure is key to deciphering immune cell communication.
  • Various antigen-presenting cells form distinct synapses with T cells.

Purpose:

  • To review recent findings on the structure of immunological synapses.
  • To compare synapses formed by T cells with different antigen-presenting cells, focusing on dendritic cells.
  • To explore parallels between immunological and nervous system synapses.

Summary:

  • The immunological synapse structure varies depending on the antigen-presenting cell type (e.g., B cell hybridoma, macrophage, dendritic cell).
  • Synapses with dendritic cells are examined in detail, alongside comparisons to neuronal synapses.

Related Experiment Videos

  • Key questions include receptor clustering mechanisms and the impact of synapse function on structure.

    • Impact:

    • Suggests dual communication modes in both immune and nervous systems: direct cell contact and soluble mediators (immunotransmitters/neurotransmitters).
    • Provides insights into immune cell interactions and potential therapeutic targets.
    • Highlights convergent principles in cell-cell communication across different biological systems.