Structure and properties of carbocyclic 5'-nor oligodeoxynucleotides
1Department of Applied Chemistry, Faculty of Engineering, Venture Business Laboratory, Ehime University, Matsuyama 790-8577, Japan.
Nucleic Acids Research. Supplement (2001)
|July 3, 2003
Abstract:
The hybridization properties of carbocyclic 5'-nor oligodeoxynucleotides 1, 2 (24 mer, B = A) with DNA and RNA were investigated by CD melting curves. These oligomers formed unstable duplexes with DNA, but formed stable duplexes with RNA selectively.
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