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Single Molecule Analysis of Laser Localized Psoralen Adducts
Published on: April 20, 2017
Quantitation of DNA damage by an aldehyde reactive probe (ARP)
1Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, Higashi-Hiroshima 739-8526, Japan.
Nucleic Acids Research. Supplement (2001)
|July 3, 2003
Abstract:
DNA is constantly damaged by endogenous and environmental agents. Abasic sites representing a major class of DNA damage can be quantitated by an ELISA-like assay using an aldehyde reactive probe (ARP). It is shown that oxidative pyrimidine lesions can be also quantitated by the ARP assay in combination with the treatment with endonuclease III.

