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Related Experiment Videos

Endoscopic evacuation of Durasphere.

Victor H Hartanto1, Deborah J Lightner, Victor W Nitti

  • 1Department of Urology, New York University School of Medicine, New York, New York 10016, USA.

Urology
|July 3, 2003
PubMed
Summary

Durasphere, a bulking agent for stress urinary incontinence, can rarely cause bladder outlet obstruction. This case details the endoscopic removal of Durasphere causing urinary retention one year post-injection.

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Bladder outlet obstruction in women: Advanced evaluation.

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Area of Science:

  • Urology
  • Biomaterials
  • Minimally Invasive Surgery

Background:

  • Stress urinary incontinence (SUI) affects numerous women, often due to intrinsic sphincter deficiency (ISD).
  • Urethral bulking agents offer a minimally invasive treatment option for SUI secondary to ISD.
  • Durasphere is a permanent injectable bulking agent composed of pyrolytic carbon-coated hollow glass microspheres.

Observation:

  • A patient developed chronic outlet obstruction and urinary retention one year after receiving Durasphere injections for SUI.
  • The obstruction was attributed to the Durasphere bulking agent within the bladder outlet.
  • Endoscopic visualization confirmed the presence of Durasphere contributing to the obstruction.

Findings:

  • Endoscopic evacuation of Durasphere was successfully performed to relieve the bladder outlet obstruction.
  • This case highlights a rare but significant complication associated with Durasphere, a permanent bulking agent.
  • The permanent nature of Durasphere necessitates careful consideration of potential long-term complications.

Implications:

  • This case underscores the importance of recognizing and managing delayed complications of urethral bulking agents.
  • Endoscopic management can be an effective treatment for Durasphere-induced bladder outlet obstruction.
  • Further research into the long-term behavior and potential complications of permanent bulking agents is warranted.

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