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Published on: December 26, 2016
[Effects of dentine phosphoprotein on remineralization of demineralized dentine]
Song-jiang Luo1, Yu-jing Li, Ling Wan
1Research Institute of Stomatology, Faculty of Stomatology, Capital Medical University, Beijing 100050, China.
Objective:
To investigate the relationship between dentine phosphoprotein (DPP) and remineralization of demineralized dentine.
Methods:
(1) Soluble DPP was extracted with 1 mol/L NaCl from demineralized dentine and was evaluated. (2) Soluble DPP was removed with 0.1 mol/L NaCl or was not removed from demineralized dentine sections in human tooth roots. Then all sections were subjected to remineralization treatment, and remineralization degrees were compared by atomic absorption spectrum, SEM and microradiography.
Results:
(1) Soluble DPP was extracted with 1 mol/L NaCl. (2) Removal of soluble DPP resulted in significantly lower calcium concentration in remineralization solution (P < 0.01), less mean light-absorbed value in demineralized dentin sections by microradiography (P < 0.01).
Conclusions:
Soluble DPP may have an inhibiting effect on remineralization of demineralized dentine, this study suggests that the remove of soluble DPP from root caries lesions may enhance their remineralization potential.
