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An improved procedure for the preparation of 8-substituted guanines
Ming Xu1, Fabio De Giacomo, Duncan E Paterson
1Laboratorium für Organische Chemie, ETH-Hönggerberg, CH-8093 Zürich, Switzerland.
Abstract:
The preparation of 8-substituted guanines using a new phosphorus(III)-mediated cyclisation of 4-acylamino-5-nitrosopyrimidines as the key step is described.
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