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Cefprozil: a review
Sumit Bhargava1, Rakesh Lodha, S K Kabra
1Department of Paediatrics, All India Insitute of Medical Sciences, Ansari Nagar, New Delhi 110029. skkabra@hotmail.com
Indian Journal of Pediatrics
|July 5, 2003
Summary
Cefprozil, a broad-spectrum cephalosporin, shows effectiveness against various bacteria and may be a good option for respiratory and skin infections. This antibiotic is safe for both children and adults.
Area of Science:
- Pharmacology and Microbiology
- Infectious Diseases
Background:
- Cefprozil is a third-generation oral cephalosporin antibiotic.
- It exhibits broad-spectrum activity against aerobic gram-negative and positive bacteria, and certain anaerobes.
Purpose of the Study:
- To evaluate the efficacy and safety of cefprozil.
- To assess its potential as an alternative treatment for common bacterial infections.
Main Methods:
- The study reviewed available data on cefprozil's properties and clinical use.
- Comparative analysis with other oral cephalosporins and beta-lactams was considered.
Main Results:
- Cefprozil demonstrates significant beta-lactamase stability against key pathogens.
- It is effective in treating mild to moderate upper and lower respiratory tract infections.
- Cefprozil is also indicated for skin and skin structure infections.
Conclusions:
- Cefprozil offers a valuable therapeutic option for various bacterial infections.
- Its safety profile is established in both pediatric and adult populations.
- It may surpass other oral cephalosporins in treating specific resistant pathogens.