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Integration host factor: putting a twist on protein-DNA recognition.
Thomas W Lynch1, Erik K Read, Aras N Mattis
1Department of Biochemistry and Molecular Biology, The University of Chicago, 920 E 58th Street CLSC 221, Chicago, IL 60637, USA.
Journal of Molecular Biology
|July 5, 2003
Summary
Integration host factor (IHF) is a DNA-binding protein. Crystal structures reveal DNA twist, not the IHF variant, dictates DNA recognition, impacting how IHF binds to its target DNA sequences.
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