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Updated: Sep 23, 2026

Surgical Porcine Model of Chronic Myocardial Ischemia Treated by Exosome-laden Collagen Patch and Off-pump Coronary Artery Bypass Graft
Published on: September 15, 2023
Minimally ischemic off-pump coronary artery bypass grafting: active perfusion-assist with nitroglycerin-supplemented
Satoshi Muraki1, Masaru Tsukamoto, Kanshi Komatsu
1Second Department of Surgery, Sapporo Medical University School of Medicine, Sapporo, Japan. muraki@sapmed.ac.jp
Abstract:
During off-pump coronary artery bypass surgery, concern remains about possible myocardial injury associated with the transient occlusion and stabilization of the target vessels. To try to minimize myocardial ischemia and achieve hemodynamic stability, we used a coronary perfusion catheter combined with the perfusion-assisted direct coronary artery bypass system, which enables active and modified coronary perfusion of the target vessel throughout the duration of multiple grafting.
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