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New taxane diterpenoids from Taiwanese Taxus sumatrana
Ya-Ching Shen1, Yu-Ling Pan, Kuang-Liang Lo
1Institute of Marine Resources, National Sun Yat-sen University, Kaohsiung, Taiwan, Republic of China. ycshen@mail.nsysu.edu.tw
Abstract:
Two new taxane diterpenoids, tasumatrols A (1) and B (2), have been isolated from extracts of the leaves and twigs of Taiwanese Taxus sumatrana. Tasumatrol A is a rare 5/6/6 taxene system, having a novel gamma-lactone at C-10 and C-19. The structures of compounds 1 and 2 were determined on the basis of two dimensional (2D)-NMR techniques, including correlation spectroscopy (COSY), 1H-detected heteronuclear multiple quantum coherence (HMQC) and heteronuclear multiple bond connectivity (HMBC) experiments.

