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[Combining artificial tears---are they always synergistic?].
T Bury1, T Bourcier, C Debbasch
1Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, 28, rue de Charenton, 75571 Paris Cedex 12. b.thierry@noos.fr
Journal Francais D'Ophtalmologie
|July 5, 2003
Summary
Artificial tears can cause thick, sticky deposits on the eyelids and conjunctiva in dry eye syndrome patients. Avoid combining Refresh artificial tears with Dacudoses or Dacryoserum washing solutions due to this risk.
Area of Science:
- Ophthalmology
- Clinical Pharmacology
Background:
- Dry eye syndrome is a common condition requiring ocular lubrication.
- Artificial tears are frequently prescribed to manage dry eye symptoms.
Observation:
- A patient using artificial tears developed unusual, thick, sticky deposits on the eyelids and conjunctiva.
- Clinical examination and experimental data corroborated the presence of these deposits.
Findings:
- The specific artificial tear product (Refresh) in combination with particular washing solutions (Dacudoses or Dacryoserum) was associated with the observed deposits.
- The deposits were characterized as thick and sticky, affecting the palpebral and conjunctival tissues.
Implications:
- Healthcare providers should be aware of potential adverse reactions with artificial tear formulations.
- Clinicians should advise patients to avoid specific combinations of artificial tears and ocular washing solutions that may cause deposits.
- Further research may be warranted to elucidate the exact mechanism of deposit formation and identify at-risk patient populations.