Managing complicated urinary tract infections: the urologic view
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Updated: Aug 12, 2026

Establishment and Characterization of UTI and CAUTI in a Mouse Model
Published on: June 23, 2015
Jonathan N Rubenstein1, Anthony J Schaeffer
1Feinberg School of Medicine, Northwestern University, Department of Urology, Tarry 11-715, 303 East Chicago Avenue, Chicago, IL 60611, USA.
Abstract:
Patients with complicated UTIs are a diverse group. These patients have upper UTIs and structural or functional abnormalities that reduce the efficacy of antimicrobial therapy. They are at increased risk for morbidity such as bacteremia and sepsis, perinephric abscess, renal deterioration, and emphysematous pyelonephritis. Appropriate urinary tract imaging, antimicrobials, medical and surgical therapies, and follow-up are required to avoid potentially devastating outcomes.
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