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Papular-purpuric "gloves and socks" syndrome caused by parvovirus B19
1Military Medical Academy, Department of Dermatology and Venereology, Belgrade.
Abstract:
This paper presents a 15-year-old boy with an acute febrile illness accompanied by purpuric and papular lesions located mostly on the dorsal areas of his hands and feet with the additional changes on his knees and elbows. Serologic studies confirmed the acute infection by parvovirus B19. Apart from mild leukocytosis there were no other abnormalities in hematologic and laboratory findings. The diagnosis of papular-purpuric "gloves and socks" syndrome (PPGSS) was made. Cutaneous changes completely resolved two weeks later. Herein the patient's condition was described together with a brief overview of the PPGSS literature concerning this relatively rare viral exanthema.
Insights
A 15-year-old boy experienced acute febrile illness with a distinctive rash, diagnosed as papular-purpuric "gloves and socks" syndrome (PPGSS). The condition was confirmed as a parvovirus B19 infection and resolved within two weeks.
Area of Science:
- Pediatrics
- Infectious Diseases
- Dermatology
Background:
- Papular-purpuric "gloves and socks" syndrome (PPGSS) is a rare viral exanthema.
- Parvovirus B19 is a known cause of various childhood illnesses.
Observation:
- A 15-year-old male presented with acute febrile illness.
- The patient exhibited characteristic purpuric and papular lesions predominantly on the dorsal hands and feet, and also on knees and elbows.
- Initial laboratory findings revealed mild leukocytosis without other significant abnormalities.
Findings:
- Serologic studies confirmed acute parvovirus B19 infection.
- The clinical presentation and diagnostic findings led to the diagnosis of papular-purpuric "gloves and socks" syndrome (PPGSS).
- The patient's cutaneous manifestations resolved completely within two weeks.
Implications:
- This case underscores the importance of considering parvovirus B19 in the differential diagnosis of PPGSS in adolescents.
- Early recognition and diagnosis of PPGSS can prevent unnecessary investigations and treatments.
- The case contributes to the literature on rare presentations of parvovirus B19 infection.