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Updated: Oct 19, 2025

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Rapid dermoscopic evolution of a Spitz nevus in an adult masquerading as melanoma
Miloš D Pavlović1, Vesna Jurčić2, James Loubser3
1Faculty of Medicine, University of Maribor, Maribor, Slovenia.
Abstract:
Spitz nevi in adults should be closely monitored. Dermoscopy is the preferred method of in vivo imaging of melanocytic nevi and may provide clues for high-risk lesions. However, there is not a perfect match between the dermoscopic image of an individual nevus, the evolution of its change, and its histopathology. We present a case of a rapidly (over months) changing and growing nevus in an adult patient with dermoscopy suggesting a melanoma but eventually with a histology of a Spitz nevus with an accompanying immune reaction.
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