Medical management of soft tissue sarcomas

Local therapies for STS, including aggressive surgical resection and radiation therapy, have improved dramatically over the last 10 years. This has resulted in improvement of important clinical outcomes such as enhanced rates of local control and higher quality of life for patients. Systemic therapy for STS, although efficacious to a certain degree, remains investigational. A major task for oncologists will be to measure accurately the single-agent activity of drugs and to integrate promising agents into multiagent regimens. This approach may allow significant progress in the management of STS in canine and feline patients.