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Acute pustular psoriasis complicated by leukocytoclastic vasculitis
1University of Chicago, Dept of Medicine-Section of Dermatology, 5841 S. Maryland, MC 5067, Chicago, IL 60637-1470, USA. mjudew@hotmail.com
Journal of Drugs in Dermatology : JDD
|July 11, 2003
Summary
A woman developed acute pustular psoriasis triggered by hydroxychloroquine and steroids. Her condition worsened with leukocytoclastic vasculitis, possibly due to levofloxacin.
Area of Science:
- Dermatology
- Internal Medicine
Background:
- Acute pustular psoriasis is an inflammatory skin condition characterized by erythema and pustules.
- Known triggers include medications, infections, pregnancy, and stress.
Observation:
- A case report details a woman experiencing acute pustular psoriasis onset.
- The condition was precipitated by hydroxychloroquine therapy and systemic steroids.
Findings:
- The patient developed widespread pustules and erythema.
- Leukocytoclastic vasculitis was observed, potentially linked to levofloxacin use.
Implications:
- This case highlights potential drug-induced pustular psoriasis and vasculitis.
- Awareness of these adverse drug reactions is crucial for patient management.