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Impact of Intermittent Fasting, Keto Diet vs Continuous Caloric Restriction on Psoriasis Severity: A Systematic
Journal of Drugs in Dermatology : JDD
|August 5, 2026
Summary
Continuous daily caloric restriction (CCR) and ketogenic diets (Keto) significantly improved psoriasis severity more than intermittent fasting (IF). These dietary strategies may offer personalized approaches for managing this chronic skin condition.
Area of Science:
- Dermatology
- Metabolic Health
- Nutrition Science
Background:
- Psoriasis is a chronic inflammatory skin disease linked to metabolic issues and obesity.
- Dietary interventions like continuous daily caloric restriction (CCR), intermittent fasting (IF), and ketogenic diets (Keto) may improve psoriasis via weight loss and immune-metabolic changes.
Purpose of the Study:
- To compare the effectiveness of IF, Keto, and CCR in reducing psoriasis severity.
Main Methods:
- Systematic review and meta-analysis.
- Evaluated changes in Psoriasis Area and Severity Index (PASI), quality of life (DLQI), and metabolic scores.
- Assessed outcomes at baseline and various follow-up times.
Main Results:
- Keto and CCR interventions showed significant decreases in PASI scores, associated with 10-25.6 kg weight loss.
- Intermittent fasting (IF) resulted in less weight loss (0-2 kg) and a smaller impact on PASI scores.
- No serious adverse effects were reported across all dietary interventions.
Conclusions:
- CCR and Keto were more effective than IF in managing psoriasis severity.
- Study limitations include heterogeneity and lack of head-to-head comparisons.
- Personalized dietary plans may complement psoriasis treatment.
