Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

GERD 2003 -- a consensus on the way ahead.

Steven F Moss1, David Armstrong, Rudi Arnold

  • 1Brown University, Providence, R.I., USA.

Digestion
|July 11, 2003
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Seeking gastroenterological services during a pandemic: lessons from a large, national, population-based survey during the COVID-19 pandemic.

Journal of the Canadian Association of Gastroenterology·2026
Same author

Small intestinal microbial fiber metabolism dysfunction in celiac disease.

Nature communications·2026
Same author

Study protocol for a multiarm, randomized controlled trial to determine the effectiveness of community-based frailty rehabilitation to improve physical function in older adults: The OPTIMAL Fitness Trial.

PloS one·2026
Same author

Patient preferences in managing zinc deficiency in celiac disease: Insights to inform future clinical trial design.

Nutrition and health·2026
Same author

Research Code Sharing in Support of Gold Standard Science.

Journal of diabetes science and technology·2026
Same author

Interobserver agreement for the assessment of erosive reflux esophagitis: a post hoc analysis of clinical trial data.

Diseases of the esophagus : official journal of the International Society for Diseases of the Esophagus·2026

Gastroesophageal reflux disease (GERD) management faces challenges in understanding prevalence, symptom correlation, and treatment effectiveness. New diagnostic tools and therapies are needed for better patient outcomes.

Area of Science:

  • Gastroenterology
  • Public Health
  • Esophageal Diseases

Background:

  • Gastroesophageal reflux disease (GERD) is a growing public health concern due to high healthcare costs, reduced quality of life, and increasing rates of esophageal adenocarcinoma.
  • Current understanding of GERD's rising prevalence and its underlying pathophysiology remains limited.
  • Challenges exist in correlating patient-reported symptoms with objective measures of gastroesophageal reflux.

Purpose of the Study:

  • To review current challenges in managing GERD and its complications.
  • To explore potential approaches for improving GERD management.
  • To highlight the need for advanced diagnostic and therapeutic strategies.

Main Methods:

  • Literature review of current GERD research and clinical practices.

Related Experiment Videos

  • Analysis of existing diagnostic and therapeutic modalities for GERD.
  • Discussion of emerging trends and future directions in GERD management.

    • Main Results:

    • Proton pump inhibitors are effective acid suppressors but do not resolve all symptoms for many patients.
    • Current pharmacological options to improve lower esophageal sphincter pressure or motility are lacking.
    • Surgical and endoscopic interventions for GERD have limitations, including morbidity, mortality, and experimental status.
    • Screening and surveillance protocols for Barrett's esophagus are contentious and require further development.

    Conclusions:

    • There is a critical need for improved methodologies to assess GERD pathophysiology and treatment efficacy.
    • Development of novel pharmacological agents and refined surgical/endoscopic techniques is essential.
    • Standardized approaches for screening and surveillance of Barrett's esophagus are required to address this contentious issue.