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Isolation of Human Islets from Partially Pancreatectomized Patients
Published on: July 30, 2011
A patient with primary biliary cirrhosis complicated with slowly progressive insulin-dependent diabetes mellitus
Hiroki Nakasone1, Kazushi Kinjo, Masaaki Yamashiro
1Okinawa Kenritsu Hokubu Hospital, Okinawa.
Abstract:
We report a case of primary biliary cirrhosis (PBC) complicated by slowly progressive insulin-dependent diabetes mellitus (SPIDDM). A 67-year-old woman was diagnosed as having PBC based on clinical manifestations and a positive result of anti-mitochondrial antibody. Furthermore, SPIDDM was diagnosed by her clinical course and a positive result of anti-glutamic acid decarboxylase antibody. Both PBC and SPIDDM are considered to be autoimmune diseases. However, the coexistence of PBC and SPIDDM is extremely rare. Liver cirrhosis sometimes accompanies hyperglycemia. When the etiology of liver cirrhosis is an autoimmune disorder such as PBC, SPIDDM should be considered as a cause of hyperglycemia.
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