Survival rates with coronary artery disease for black women compared with black men

Y Liao1, R S Cooper, J K Ghali

  • 1Department of Preventive Medicine and Epidemiology, Loyola University Medical Center, Maywood, IL 60153.

JAMA
|October 14, 1992
PubMed

Insights

Black women with coronary heart disease have similar survival rates to black men. However, women face a worse prognosis compared to men without the disease.

Area of Science:

  • Cardiology
  • Public Health
  • Health Disparities

Background:

  • Coronary heart disease (CHD) affects diverse populations, with potential disparities in outcomes.
  • Understanding gender-specific prognosis in black patients with CHD is crucial for targeted interventions.

Purpose of the Study:

  • To investigate the influence of gender on the prognosis of coronary heart disease (CHD) specifically within the black patient population.

Main Methods:

  • A cohort study was conducted using a consecutive sample from a hospital registry in Chicago, IL.
  • Included were 1719 black patients (780 men, 939 women) undergoing cardiac catheterization, hospitalization for acute myocardial infarction, or coronary artery bypass grafting.
  • Follow-up averaged 4 years, with adjusted analyses for various risk factors.

Main Results:

  • Overall mortality rates for acute myocardial infarction and coronary artery bypass grafting were similar between men and women.
  • Relative risks for cardiac death showed no significant difference between women and men for CHD, myocardial infarction, or bypass grafting after adjustments.
  • However, compared to same-sex individuals without CHD, women had substantially higher relative risk estimates for adverse outcomes than men.

Conclusions:

  • Prognosis for black women with coronary heart disease is comparable to that of black men.
  • Black women with CHD have a considerably worse prognosis relative to same-sex individuals without the disease, compared to men.
Abstract

Related Concept Videos

X-linked Traits01:19

X-linked Traits

In most mammalian species, females have two X sex chromosomes and males have an X and Y. As a result, mutations on the X chromosome in females may be masked by the presence of a normal allele on the second X. In contrast, a mutation on the X chromosome in males more often causes observable biological defects, as there is no normal X to compensate. Trait variations arising from mutations on the X chromosome are called “X-linked”.
Disorders of the Male Reproductive System01:20

Disorders of the Male Reproductive System

Men's health issues are increasingly recognized as significant, with several conditions posing common threats. Among these, testicular cancer is especially prevalent in younger men, particularly those aged 20 to 35 years. The disease often manifests as a painless mass in the testicles, sometimes accompanied by a sensation of heaviness or a dull ache.
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Comparing the Survival Analysis of Two or More Groups01:20

Comparing the Survival Analysis of Two or More Groups

Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and Cox...
Mitral Stenosis I: Introduction01:22

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...