Bilateral combined retinal and choroidal detachment in antineutrophil cytoplasmic antibody-positive scleritis

To describe a rare complication of scleritis in a patient with positive serum antineutrophil cytoplasmic antibodies (ANCA).

We present a case report of a patient who developed bilateral retinal and choroidal detachment associated with ANCA-positive scleritis.

Oral steroids alone were insufficient to maintain sustained remission of ocular inflammation. Clinical relapse of the scleritis was associated with ANCA titres becoming positive again. A combination of cyclophosphamide and steroids was successful in achieving control of the intraocular inflammation over a follow-up period of 18 months.

Bilateral combined retinal and choroidal detachment is a potentially blinding complication of ANCA-positive scleritis. Monitoring of ANCA titres is useful in the management of the disease.