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A neuro-Behcet's lesion in oculomotor nerve nucleus
1Department of Neurosurgery, Medical Faculty, Atatürk University, Erzurum, Turkey.
Acta Neurologica Scandinavica
|July 16, 2003
Summary
Nuclear involvement of the oculomotor nerve in Behcet's disease is rare. Oculomotor nerve palsy may persist despite radiological improvement in neuro-Behcet's disease.
Area of Science:
- Neuro-ophthalmology
- Autoimmune diseases
Background:
- Behcet's disease is a multisystemic inflammatory disorder.
- Oculomotor nerve (cranial nerve III) involvement can occur, but typically fascicular, not nuclear.
Observation:
- A 25-year-old woman with Behcet's symptoms presented with left eye issues including ptosis, mydriasis, and gaze palsy.
- Magnetic resonance imaging revealed an inflammatory lesion in the left oculomotor nerve nucleus.
Findings:
- Neuro-Behcet's disease was diagnosed.
- Treatment with dexamethasone led to normalization of mucocutaneous lesions and lab abnormalities.
- Oculomotor nerve palsy persisted despite radiological improvement.
Implications:
- This case highlights the possibility of nuclear oculomotor nerve involvement in Behcet's disease.
- Clinical deficits may remain even when imaging shows resolution of inflammation.
- Persistent oculomotor nerve palsy can occur in neuro-Behcet's disease.