Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A 5-microm filter does not reduce propofol-induced pain.

C Hellier1, S Newell, J Barry

  • 1James Cook University, Department of Anaesthesia and Intensive Care, Cairns Base Hospital, The Esplanade, Cairns 4870, Australia.

Anaesthesia
|July 16, 2003
PubMed
Summary

A 5-microm filter does not reduce pain from propofol injections. This study found no significant difference in pain scores when using filters versus unfiltered needles for propofol administration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Life stage-specific marine migration and spatial behaviour of sea trout (Salmo trutta) from two coastal rivers.

Journal of fish biology·2025
Same author

Comparative before-after study of fever prevention versus targeted temperature management following out-of-hospital cardiac arrest.

Resuscitation plus·2024
Same author

The implementation of a public health alcohol policy in Ireland.

Irish journal of psychological medicine·2023
Same author

Detailed analysis of in-hospital transmission of SARS-CoV-2 using whole genome sequencing.

The Journal of hospital infection·2022
Same author

Safety of the use of gold nanoparticles conjugated with proinsulin peptide and administered by hollow microneedles as an immunotherapy in type 1 diabetes.

Immunotherapy advances·2022
Same author

Effect of feeding single-dam or pooled colostrum on maternally derived immunity in dairy calves.

Journal of dairy science·2021

Area of Science:

  • Anesthesiology
  • Pharmacology

Background:

  • Propofol injection commonly causes pain.
  • The use of filters to mitigate this pain is debated.
  • Potential mechanisms include contaminant removal or altered flow dynamics.

Purpose of the Study:

  • To evaluate the efficacy of a 5-microm filter in reducing propofol-induced pain.
  • To determine if pain reduction is linked to contaminant removal or flow characteristic changes.

Main Methods:

  • 120 women (ASA 1-3, 18-70 years) were randomized into three groups.
  • Group A: unfiltered cannula. Group B: filter needle for aspiration, unfiltered cannula for injection.
  • Group C: filter needle for aspiration and injection. Propofol administered at 0.5 ml/s.

Related Experiment Videos

Main Results:

  • No significant difference in pain frequency or severity was observed among the three groups.
  • The use of a 5-microm filter did not alter the patient-reported pain experience.
  • Contaminant removal or flow alteration did not appear to influence pain perception.

Conclusions:

  • A 5-microm filter is ineffective in reducing pain associated with propofol injection from a rubber-stoppered vial.
  • The study did not support the hypothesis that filters alleviate propofol-induced pain through contaminant removal or flow modification.